What is Medik8 Advanced Night Restore Medik8 Advanced Night Restore has been clinically proven to smooth the appearance of stubborn lines and wrinkles in just 7 days. This signature night cream leaves skin feeling plump and pillow-soft. While you sleep, the ceramide-rich formula deeply nourishes and visibly firms your complexion, delivering youth-boosting results while supporting your skin's natural barrier. By replenishing essential lipids lost over time, Advanced Night Restore provides maximum comfort along with a visible plumping and firming effect. It's expertly designed to be used after vitamin A (retinol or retinal) in the evening.